Metabolism and Energy balance, The brain controls food Intake
The Brain controls food intake and not the digestive system. The hypothalamus has two food centers that control food intake: feeding centre - satiety centre - stops food intake by inhibiting the feeding centre Two Theories for regulation of food intake: Glucostatic Theory. Glucose utilised by the hypothalamic centers regulates food intake. Increased glucose concentration stimulates the satiety centre that inhibits the feeding centre. Decrease in clucose concentration inhibits the satiety centre and stimulates the feeding centre. Lipostatic theory. Signal from the fat stores regulates food intake to maintain a particular weight. Leptin - a protein hormone synthesized and released from adipocytes under influence of the OBESE GENE, evidences the negative feedback from fat cells to the brain. Leptin inhibits Neuropeptide Y (NPY) in a negative feedback pathway Neuropeptide Y (NPY), a brain neurotransmitter that stimulates food intake....