The Skin - Pathology
Pathology of the skin is basically the same as those that occur in other organs. The changes that can be seen with the naked eye correlates well with that seen microscopically. The evolution of skin lesions can be readily followed by repeated biopsy. The major functions of skin include sensory perception, protection against mechanical trauma, UV light and infection, insulation and temperature control, conservation of fluid, biosynthesis and excretion and aesthetic function. The morphology of the skin that appears simple at first sight is as complex and diverse as the 10 major functions of the skin - depending on the site, sex, age, race and environment. Skin Biopsy: Select a site - not too early or too late but a fairly early representative lesion. Full thickness skin including the subcutaneous fat. The tissue is not to be grasped with forceps but a Gillies Hook (see below) to raise and maintain tension on the skin during removal. Orientating the...