SA Medical - General Medicine And Imaging of Disease

There are 2 regulatory hormones, Parathyroid Hormone and calcitonin. CALCIUM AND PHOSPHATE IN THE EXTRACELLULAR FLUID AND THE PLASMA FUNCTION OF VITAMIN D. CONTROL OF VITAMIN D FORMATION The active form of Vitamin D 1,25-dihydroxycholecalceferol is regulated via the following steps In the skin: 7-dehyrocholesterol is conveted by UV light to Vitamin D3 In the liver:  Vitamin D3 is converted to 25-hydroxycholecalciferol In the cortex of the kidney:  25-hydroxycholecalciferol is converted to 1,25-dihydroxycholecalceferol in reaction stimulated and controlled by PTH. PTH formation is stimulated by a reduction in ECF Calcium concentration, formation of 1,25-dihyroxycholecalcepherol also increases when Calium concentration in the ECF drops GASTROINTESTINAL CALCIUM ABSORPTION - 1,25-DIHYDROXYCHOLECALCIFEROL stimulates the intestinal epithelium of the small intestine to form calcium binding protein, calcium stimulated ATPase and Alkaline phosphatase, all which prom...

Dear patients Thank you for your most interesting questions and thank you for trusting me to manage you health. This is an interesting question. To answer these question we need to talk about Calcium, phosphate and magnesium in the Human Body. Calcium content of the body depends on the balance between the intestinal calcium from diet and the calcium lost in your faeces (shit) and urine (pee). Intestinal (GUT) uptake and loss The amount of calcium that is absorbed is dependent on Amount of calcium (Ca2+) available.  Acid pH increases calcium and alkalinity promotes complex formation and diminishes absorption.  The following reduce your calcium absorption: Uncooked beans - phytates and Oxalytes - chocolate, nuts and berries - and tea Active Vitamin D Kidney The kidney filters 250mmol of Calcium each day, 95% are reabsorbed in the tubules. The majority is taken up in the proximal tubules without hormonal regulation, while fine adjustment is require...